New cell of origin for optic gliomas identified
Author: Washington University
Published On: 08/22/2017
Children with Neurofibromatosis type 1 (NF1) are prone to the development of low-grade brain tumors affecting the nerve carrying vision to the brain, called the optic nerve. Where these tumors come from has been a matter of scientific debate. Using new genetic modeling strategies, recent studies indicate that optic gliomas can arise from two different cell types.
Anne Solga, PhD, a former graduate student in the laboratory of Dr. David Gutmann, working with her colleagues in the NF Center and the University of California-San Diego, now report that optic gliomas develop from both neural stem cells and progenitor cells.
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