By combining years of experience making human stem cells into tiny brain-like structures called organoids, or “mini-brains” and growing patient-derived brain tumor cells, Enquan Xu and colleagues found the perfect conditions to make real pediatric brain tumor cells grow inside healthy mini-brains.

Researchers at Cincinnati Children's have identified a potential new way to relieve chronic pain linked to NF1. The new findings suggest that pain in NF1 may begin before tumors appear and may be driven by abnormal signaling from Schwann cells, which normally support and protect nerves.

Every year, SketchNF gives children and teens living with NF a platform to share their creativity, tell their stories, and inspire others through art. From toddlers like Everly, who is undergoing chemotherapy for an optic pathway glioma, to older participants like Connor, who continue to navigate the challenges of NF, these young artists remind us that NF does not define them.

Meet Rachel Pereira, a first-grade teacher at Stanford Elementary School whose resilience and compassion earned her the title of Teacher of the Year. Living with NF1, visible plexiform neurofibromas, and surviving breast cancer, Rachel is using her journey to teach her students one of life's most important lessons: true character is found on the inside.