Groundbreaking Research on MPNSTs to be Discussed in Upcoming Virtual Meeting

Author: NF Network

Published On: 12/3/25

In an exciting development for the neurofibromatosis (NF) community, Project Dream, an initiative launched by NF Network in 2023, has made strides in funding innovative research focused on high-potential NF projects. With a funding goal of $250,000 for the year, the program has successfully financed three promising projects and aims to support two additional initiatives while building reserves for future endeavors.

One of the awarded researchers, Dr. Angela Hirbe, an Associate Professor of Medicine and Pediatrics and the Director of the Adult Neurofibromatosis Clinical Program at Washington University School of Medicine, is set to present her groundbreaking research in a free virtual meeting scheduled for December 17.

Dr. Hirbe's research focuses on malignant peripheral nerve sheath tumors (MPNSTs), a particularly aggressive form of cancer that predominantly impacts individuals with neurofibromatosis type 1 (NF1). Her study explores the influence of an extra copy of chromosome 8 on both the development of MPNSTs and the resistance of these tumors to treatment. 

By delving into how this genetic alteration affects cell behavior and drug responses, Dr. Hirbe aims to identify new targeted therapies that could enhance survival rates for patients battling this challenging condition.

The virtual meeting promises to shed light on this critical work and inform attendees about the promising direction of research in the field of neurofibromatosis. Stakeholders, supporters, and anyone interested in the latest advancements in NF research are encouraged to attend and learn more about the potential implications of Dr. Hirbe's findings. 

For those interested in joining the meeting and supporting ongoing research efforts, you can register here.

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